The Clemson Tigers defeated the Wake Forest Demon Deacons 37-13 in their ACC college football opener. Quarterback Trevor Lawrence threw for 351 yards and a touchdown, and rushed for 2 touchdowns in the win. Running back Travis Etienne rushed for 102 yards and a touchdown, and caught 3 passes for 47 yards. The Tigers defense had 6 sacks, led by Miles Murphy with 2.